How much weight could I lose using Alli?

Alli may help you lose weight, but the weight loss will likely be modest — perhaps just a few pounds more than you would lose with diet and exercise alone.

More than 40 percent of people taking Alli while following a calorie-restricted diet and increasing physical activity lost 5 percent or more of their body weight within a year. Clinically meaningful weight loss — enough weight loss to begin lowering the risk of cardiovascular disease, diabetes and other diseases — is generally defined as 5 percent or more of body weight.

People who ate a calorie-restricted diet, exercised regularly and took Alli lost an average of 5.7 pounds (2.6 kilograms) more in one year than did people who only dieted and exercised.